Nucleofill In London

nucleofill London

What is Nucleofill?

Nucleofill is an innovative skincare product containing a high concentration of polynucleotides (PN), designed for deep hydration, antioxidant protection, cell regeneration, and enhancing skin barrier function. Administered through injection therapy, Nucleofill helps achieve firmer, more youthful-looking skin.

See our clinic



The unique aspect of this technology is its low heat output, significantly reducing post-treatment redness and recovery time. Due to its non-invasive and effective nature, CoolPeel is an ideal choice for those seeking skin rejuvenation.


Nucleofill improves skin texture and elasticity, reducing fine lines and wrinkles. Injection sites include the eye area, face, neck and body, making it suitable for individuals seeking deep repair and anti-aging benefits.


Nucleofill Consultation

Book a consultation for Nucleofill to improves skin texture and elasticity, reducing fine lines and wrinkles. Injection sites include the eye area, face, neck and body.



  • How long will it last?

    Nucleofill,typically lasts between 6 to 12 months. The duration can vary based on several factors, including the individual's skin type, age, lifestyle, and the area being treated. For optimal results, a series of initial treatments followed by maintenance sessions is often recommended.

  • Is it Painful?

    Most patients report feeling only mild discomfort or a slight stinging sensation during the injection. To minimize discomfort, a topical anesthetic cream is often applied to the treatment area before the procedure.

  • Recovery & Down Time

    After the treatment, some mild swelling, redness, or tenderness at the injection sites can occur, but these side effects typically subside within a few days.

  • Who will perform the treatment

    You will be treated by one of our senior aesthetic practitioner. They will help you decide whether this is the right treatment for you at the consultation.

The procedure

The treatment area will be cleaned thoroughly to remove any makeup, dirt, or oils.

A topical anaesthetic cream may be applied to the area to minimise any discomfort during the injection process. 

Nucleofill is administered through a series of small injections using a fine needle or cannula.

The product is injected into the dermis or subcutaneous layer of the skin, depending on the specific areas being treated.

The practitioner may use different injection techniques to ensure even distribution of the product and to target specific areas of concern.


Highly Skilled Professionals:

The Yuki Clinic only allocates practising privileges to medical professionals who have prescribing rights. So your treatments will only be performed by cosmetic surgeons, aesthetic doctors or nurse practitioners. Professionals such as these can, consult, prescribe, treat, and manage your safety and care.

Service & Care:

The safety and wellbeing of our patients are most important to us. We create an experience that goes beyond your treatment with your clinician. Your patient journey begins with booking your appointment right through to your aftercare. With a strong passion and wealth of experience in the aesthetics industry, our team looks forward to welcoming you to Yuki Clinic.

FDA Approved Products:

For all of our treatment’s we use only premium and FDA approved products. All skincare products are medical grade and require a prescription through consultation with one of our medical professionals.

Patient Satisfaction:

The heart of our clinic is our patients. Receiving positive feedback is the most rewarding award we can receive. At the Yuki Clinic, we take all feedback very seriously and use this to help improve our treatments and services.

Clinic Location:

Located in the heart of Oxford Circus, you’ll find The Yuki Clinic right next door to Top Shop, All Saints and Urban Outfitters. Across the road from the clinic, you’ll find the world-renowned Elan Café. Elan Café is the perfect spot to grab a coffee and a cake before a treatment.

The nearest tube station is Oxford Circus, London. After you exit Oxford Circus Station, cross Oxford Street and walk 2 minutes to the clinic. So easy!

Contact US

For more information please call

The Yuki Clinic London

6-10 Great Portland Streeet, London, W1W 8QL